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• Lab-on-a-chip advance is promising for researchers - Johns Hopkins News-Letter

Lab-on-a-chip advance is promising for researchers
Johns Hopkins News-Letter, MD - Nov 20, 2008
... signaling proteins is live cell imaging, which uses fluorescent markers to tag a signaling protein of interest and visualizes them under microscopy. ...
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• 'Powerhouses' From Living Cells -- Mitochondria -- Power New Explosives Detector
Researchers in Missouri have borrowed the technology that living cells use to produce energy to develop a tiny, self-powered sensor for rapid detection of hidden explosives. The experimental sensor, about the size of a postage stamp, represents the first of its kind to be powered by mitochondria, the microscopic "powerhouses" that provide energy to living cells, the researchers say.
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• Scientists discover new compounds to target muscular dystrophy
Using a drug-discovery technique in which molecules compete against each other for access to the target - the strand of toxic RNA that causes the most common form of muscular dystrophy in adults - a team at the University of Rochester Medical Center has identified several compounds that, in the laboratory, block the unwanted coupling of two molecules that is at the root of the disease.
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• Making mouse knockouts en masse, the science of sun tanning, and silencing jumping genes
Includes interviews with Dr Francis Collins on the international mouse knockout program, Dr David Fisher on the role of p53 in tanning, and Dr Greg Hannon on pi RNAs silence transposons in the fly genome.
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• Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells
NEP/CALLA or CD10 is an endopeptidase (E.C. 3.4.24.11) that inactivates numerous neuropeptides, including dynorphin. Dynorphin is an endogenous opioid polypeptide that binds to [kappa]-opioid receptors with greatest affinity. R1.1 mouse thymoma cells highly express [kappa]-opioid receptors. In this study, on R1.1 cells, NEP activity was inhibited by [kappa]-opioid polypeptide dynorphin (10-8-10-6 M) and by thiorphan (2 × 10-4 M), a known inhibitor of NEP (30 min treatment). NEP inhibition by dynorphin was stronger than by thiorphan. A non-opioid opioid mechanism of action was mostly involved in this inhibition. Copyright © 2008 John Wiley & Sons, Ltd.
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• Triplantanol increases plant cell growth
Plants that are growing most vigorously exhibit the most noticeable effect on leaf growth. There can be both length and width increases in plant leaves. This is often accompanied by increased thickness and robustness. Leaves can become more fuller and more rounded according to leaf form and plant type. See the pictues on our site (Bigger leaves) showing how leaf shape has been changed in Geraneum plants
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Live Search: picture of redblood cell
By editor@news-medical.net - Copyright © 2008 Microsoft. All rights reserved. These XML results may not be used, reproduced or transmitted in any manner or for any purpose other than rendering Live Search results within an RSS aggregator for your personal, non-commercial use. Any other use of these results requires express written permission from Microsoft Corporation. By accessing this web page or using these results in any manner whatsoever, you agree to be bound by the foregoing restrictions. - version: v1.5 build A